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Remember that during this era aromatase inhibitors did not exist, so bodybuilders were always searching for a steroid that would produce results without the estrogenic risks.

Mesterolone had seen widespread use in body building primarily for antiestrogenic activity in anabolic steroid stacks but such use has declined after introduction of aromatase inhibitors and SERMs. Use in puberty may cause premature closure of the epiphyses and stop linear growth.

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